{"id":3547,"date":"2024-06-13T11:03:11","date_gmt":"2024-06-13T09:03:11","guid":{"rendered":"https:\/\/stopalzheimer.be\/?p=3547"},"modified":"2024-09-10T14:58:01","modified_gmt":"2024-09-10T12:58:01","slug":"des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie","status":"publish","type":"post","link":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/","title":{"rendered":"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie"},"content":{"rendered":"\n

Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie<\/h2>\n\n\n\n

R\u00e9cemment, les chercheurs du centre de recherche VIB-KU Leuven Center for Brain &
Disease Research<\/a>, dirig\u00e9s par le Prof. Wim Annaert, pr\u00e9sident de notre conseil scientifique<\/a>, ont
r\u00e9alis\u00e9 une d\u00e9couverte majeure dans le domaine de la recherche sur la maladie d\u2019Alzheimer. Cette avanc\u00e9e prometteuse a \u00e9t\u00e9 rendue possible gr\u00e2ce \u00e0 un financement de notre Fondation.<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Dans une r\u00e9cente \u00e9tude ayant \u00e9t\u00e9 financ\u00e9e gr\u00e2ce \u00e0 votre g\u00e9n\u00e9rosit\u00e9, les chercheurs du centre de recherche VIB-KU Leuven Center for Brain & Disease Research, dirig\u00e9s par le Prof. Wim Annaert, pr\u00e9sident de notre conseil scientifique, ont mis en lumi\u00e8re un nouveau m\u00e9canisme potentiellement li\u00e9 aux stades pr\u00e9coces de la maladie d\u2019Alzheimer. Ils ont d\u00e9couvert qu\u2019un fragment de la prot\u00e9ine pr\u00e9curseur de l\u2019amylo\u00efde (APP), appel\u00e9 APP-CTF, perturbe la communication entre les compartiments cellulaires cruciaux pour le stockage du calcium et l\u2019\u00e9limination des d\u00e9chets. Cette perturbation pourrait \u00e9ven\u0002tuellement entra\u00eener la mort des cellules neurales, contribuant ainsi au d\u00e9veloppement de la maladie.<\/p>\n\n\n\n

Les r\u00e9sultats de cette recherche ont \u00e9t\u00e9 publi\u00e9s en avril dans le prestigieux journal scientifique Developmental Cell, mettant en lumi\u00e8re l\u2019importance et la port\u00e9e de cette d\u00e9couverte. Wim Annaert, Pr\u00e9sident du conseil scientifique de notre Fondation, exprime sa satisfaction : \u00ab Nous sommes tr\u00e8s heureux de cette avanc\u00e9e. Cela pourrait avoir des implications importantes pour le d\u00e9veloppement de nouveaux traitements sur la maladie d\u2019Alzheimer.<\/strong> <\/em>\u00bb <\/p>\n\n\n\n

En effet, cette d\u00e9couverte rev\u00eat une importance particuli\u00e8re dans la compr\u00e9hension des m\u00e9canismes sous-jacents \u00e0 la maladie d\u2019Alzheimer. Alors que la maladie se caract\u00e9rise par une perte progressive des
fonctions cognitives et des changements de comportement, cette recherche sugg\u00e8re l\u2019existence d\u2019\u00e9v\u00e9nements encore plus pr\u00e9coces dans le cerveau des patients, avant m\u00eame la formation des plaques
amylo\u00efdes. \u00ab Nous avons identifi\u00e9, dans le cadre de cette recherche financ\u00e9e par Stop Alzheimer,
que les APP-CTF, r\u00e9sultant de la suppressionde la gamma-s\u00e9cr\u00e9tase, perturbent l\u2019\u00e9quilibre d\u00e9licat du calcium \u00e0 l\u2019int\u00e9rieur des lysosomes. <\/em>\u00bb explique le Professeur. Il ajoute \u00e9galement que c\u2019est cette perturbation qui entra\u00eene l\u2019accumulation de cholest\u00e9rol et r\u00e9duit la capacit\u00e9 des lysosomes \u00e0 d\u00e9grader les d\u00e9chets cellulaires, compromettant ainsi la sant\u00e9 neuronale.<\/p>\n\n\n\n

Ces d\u00e9couvertes ouvrent ainsi la voie \u00e0 de nouvelles approches th\u00e9rapeutiques pour les stades pr\u00e9coces de la maladie d\u2019Alzheimer. En ciblant sp\u00e9cifiquement l\u2019\u00e9limination des APP-CTF toxiques, sans bloquer compl\u00e8tement l\u2019enzyme, il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie R\u00e9cemment, les chercheurs du centre de recherche VIB-KU Leuven Center for Brain &Disease Research, dirig\u00e9s par le Prof. Wim Annaert, pr\u00e9sident de notre conseil scientifique, ontr\u00e9alis\u00e9 une d\u00e9couverte majeure dans le domaine de la recherche sur la maladie d\u2019Alzheimer. Cette avanc\u00e9e […]<\/p>\n","protected":false},"author":3,"featured_media":3548,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[29],"tags":[],"locatie":[],"class_list":["post-3547","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-onderzoek"],"acf":[],"yoast_head":"\nDes chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie - Stop Alzheimer<\/title>\n<meta name=\"description\" content=\"Il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie d'Alzheimer gr\u00e2ce \u00e0 cette d\u00e9couverte.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie - Stop Alzheimer\" \/>\n<meta property=\"og:description\" content=\"Il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie d'Alzheimer gr\u00e2ce \u00e0 cette d\u00e9couverte.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/\" \/>\n<meta property=\"og:site_name\" content=\"Stop Alzheimer\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/StichtingAlzheimerOnderzoek\/\" \/>\n<meta property=\"article:published_time\" content=\"2024-06-13T09:03:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-09-10T12:58:01+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2024\/06\/20221215_143941-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lucie\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschreven door\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lucie\" \/>\n\t<meta name=\"twitter:label2\" content=\"Geschatte leestijd\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/\"},\"author\":{\"name\":\"Lucie\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#\\\/schema\\\/person\\\/a4bfa7bb02bcf39e27ec3b315c293e22\"},\"headline\":\"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie\",\"datePublished\":\"2024-06-13T09:03:11+00:00\",\"dateModified\":\"2024-09-10T12:58:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/\"},\"wordCount\":485,\"publisher\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/stopalzheimer.be\\\/wp-content\\\/uploads\\\/2024\\\/06\\\/20221215_143941-scaled.jpg\",\"articleSection\":[\"Onderzoek\"],\"inLanguage\":\"nl-NL\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/\",\"url\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/\",\"name\":\"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie - Stop Alzheimer\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/stopalzheimer.be\\\/wp-content\\\/uploads\\\/2024\\\/06\\\/20221215_143941-scaled.jpg\",\"datePublished\":\"2024-06-13T09:03:11+00:00\",\"dateModified\":\"2024-09-10T12:58:01+00:00\",\"description\":\"Il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie d'Alzheimer gr\u00e2ce \u00e0 cette d\u00e9couverte.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#breadcrumb\"},\"inLanguage\":\"nl-NL\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"nl-NL\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#primaryimage\",\"url\":\"https:\\\/\\\/stopalzheimer.be\\\/wp-content\\\/uploads\\\/2024\\\/06\\\/20221215_143941-scaled.jpg\",\"contentUrl\":\"https:\\\/\\\/stopalzheimer.be\\\/wp-content\\\/uploads\\\/2024\\\/06\\\/20221215_143941-scaled.jpg\",\"width\":2560,\"height\":1920},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/stopalzheimer.be\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#website\",\"url\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/\",\"name\":\"Stop Alzheimer\",\"description\":\"Stichting Alzheimer Onderzoek\",\"publisher\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"nl-NL\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#organization\",\"name\":\"Stop Alzheimer\",\"url\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"nl-NL\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/stopalzheimer.be\\\/wp-content\\\/uploads\\\/2025\\\/04\\\/241021_Alzheimer_logoNL_NEW.png\",\"contentUrl\":\"https:\\\/\\\/stopalzheimer.be\\\/wp-content\\\/uploads\\\/2025\\\/04\\\/241021_Alzheimer_logoNL_NEW.png\",\"width\":2362,\"height\":515,\"caption\":\"Stop Alzheimer\"},\"image\":{\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/StichtingAlzheimerOnderzoek\\\/\",\"https:\\\/\\\/www.youtube.com\\\/@stichtingalzheimeronderzoe3860\\\/videos\",\"https:\\\/\\\/be.linkedin.com\\\/in\\\/stichting-alzheimer-onderzoek-fondation-recherche-alzheimer-8760b61a4\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/stopalzheimer.be\\\/fr\\\/#\\\/schema\\\/person\\\/a4bfa7bb02bcf39e27ec3b315c293e22\",\"name\":\"Lucie\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"nl-NL\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a2cabf71da3f66ce28610368d66eab36ec2a054b07526e0376fc3565112668b7?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a2cabf71da3f66ce28610368d66eab36ec2a054b07526e0376fc3565112668b7?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a2cabf71da3f66ce28610368d66eab36ec2a054b07526e0376fc3565112668b7?s=96&d=mm&r=g\",\"caption\":\"Lucie\"},\"url\":\"https:\\\/\\\/stopalzheimer.be\\\/nl\\\/author\\\/lucie\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie - Stop Alzheimer","description":"Il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie d'Alzheimer gr\u00e2ce \u00e0 cette d\u00e9couverte.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/","og_locale":"nl_NL","og_type":"article","og_title":"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie - Stop Alzheimer","og_description":"Il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie d'Alzheimer gr\u00e2ce \u00e0 cette d\u00e9couverte.","og_url":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/","og_site_name":"Stop Alzheimer","article_publisher":"https:\/\/www.facebook.com\/StichtingAlzheimerOnderzoek\/","article_published_time":"2024-06-13T09:03:11+00:00","article_modified_time":"2024-09-10T12:58:01+00:00","og_image":[{"width":2560,"height":1920,"url":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2024\/06\/20221215_143941-scaled.jpg","type":"image\/jpeg"}],"author":"Lucie","twitter_card":"summary_large_image","twitter_misc":{"Geschreven door":"Lucie","Geschatte leestijd":"3 minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#article","isPartOf":{"@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/"},"author":{"name":"Lucie","@id":"https:\/\/stopalzheimer.be\/fr\/#\/schema\/person\/a4bfa7bb02bcf39e27ec3b315c293e22"},"headline":"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie","datePublished":"2024-06-13T09:03:11+00:00","dateModified":"2024-09-10T12:58:01+00:00","mainEntityOfPage":{"@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/"},"wordCount":485,"publisher":{"@id":"https:\/\/stopalzheimer.be\/fr\/#organization"},"image":{"@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#primaryimage"},"thumbnailUrl":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2024\/06\/20221215_143941-scaled.jpg","articleSection":["Onderzoek"],"inLanguage":"nl-NL"},{"@type":"WebPage","@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/","url":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/","name":"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie - Stop Alzheimer","isPartOf":{"@id":"https:\/\/stopalzheimer.be\/fr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#primaryimage"},"image":{"@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#primaryimage"},"thumbnailUrl":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2024\/06\/20221215_143941-scaled.jpg","datePublished":"2024-06-13T09:03:11+00:00","dateModified":"2024-09-10T12:58:01+00:00","description":"Il pourrait \u00eatre possible de ralentir ou m\u00eame de pr\u00e9venir la progression de la maladie d'Alzheimer gr\u00e2ce \u00e0 cette d\u00e9couverte.","breadcrumb":{"@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#breadcrumb"},"inLanguage":"nl-NL","potentialAction":[{"@type":"ReadAction","target":["https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/"]}]},{"@type":"ImageObject","inLanguage":"nl-NL","@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#primaryimage","url":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2024\/06\/20221215_143941-scaled.jpg","contentUrl":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2024\/06\/20221215_143941-scaled.jpg","width":2560,"height":1920},{"@type":"BreadcrumbList","@id":"https:\/\/stopalzheimer.be\/nl\/des-chercheurs-belges-decouvrent-un-nouveau-mecanisme-dans-les-stades-precoces-de-la-maladie\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/stopalzheimer.be\/"},{"@type":"ListItem","position":2,"name":"Des chercheurs Belges d\u00e9couvrent un nouveau m\u00e9canisme dans les stades pr\u00e9coces de la maladie"}]},{"@type":"WebSite","@id":"https:\/\/stopalzheimer.be\/fr\/#website","url":"https:\/\/stopalzheimer.be\/fr\/","name":"Stop Alzheimer","description":"Stichting Alzheimer Onderzoek","publisher":{"@id":"https:\/\/stopalzheimer.be\/fr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/stopalzheimer.be\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"nl-NL"},{"@type":"Organization","@id":"https:\/\/stopalzheimer.be\/fr\/#organization","name":"Stop Alzheimer","url":"https:\/\/stopalzheimer.be\/fr\/","logo":{"@type":"ImageObject","inLanguage":"nl-NL","@id":"https:\/\/stopalzheimer.be\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2025\/04\/241021_Alzheimer_logoNL_NEW.png","contentUrl":"https:\/\/stopalzheimer.be\/wp-content\/uploads\/2025\/04\/241021_Alzheimer_logoNL_NEW.png","width":2362,"height":515,"caption":"Stop Alzheimer"},"image":{"@id":"https:\/\/stopalzheimer.be\/fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/StichtingAlzheimerOnderzoek\/","https:\/\/www.youtube.com\/@stichtingalzheimeronderzoe3860\/videos","https:\/\/be.linkedin.com\/in\/stichting-alzheimer-onderzoek-fondation-recherche-alzheimer-8760b61a4"]},{"@type":"Person","@id":"https:\/\/stopalzheimer.be\/fr\/#\/schema\/person\/a4bfa7bb02bcf39e27ec3b315c293e22","name":"Lucie","image":{"@type":"ImageObject","inLanguage":"nl-NL","@id":"https:\/\/secure.gravatar.com\/avatar\/a2cabf71da3f66ce28610368d66eab36ec2a054b07526e0376fc3565112668b7?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a2cabf71da3f66ce28610368d66eab36ec2a054b07526e0376fc3565112668b7?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a2cabf71da3f66ce28610368d66eab36ec2a054b07526e0376fc3565112668b7?s=96&d=mm&r=g","caption":"Lucie"},"url":"https:\/\/stopalzheimer.be\/nl\/author\/lucie\/"}]}},"_links":{"self":[{"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/posts\/3547","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/comments?post=3547"}],"version-history":[{"count":0,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/posts\/3547\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/media\/3548"}],"wp:attachment":[{"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/media?parent=3547"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/categories?post=3547"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/tags?post=3547"},{"taxonomy":"locatie","embeddable":true,"href":"https:\/\/stopalzheimer.be\/nl\/wp-json\/wp\/v2\/locatie?post=3547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}