{"id":4061,"date":"2024-11-15T09:47:55","date_gmt":"2024-11-15T08:47:55","guid":{"rendered":"https:\/\/stopalzheimer.be\/?p=4061"},"modified":"2024-11-15T09:47:56","modified_gmt":"2024-11-15T08:47:56","slug":"un-nouveau-medicament-approuve","status":"publish","type":"post","link":"https:\/\/stopalzheimer.be\/fr\/un-nouveau-medicament-approuve\/","title":{"rendered":"Un nouveau m\u00e9dicament approuv\u00e9"},"content":{"rendered":"<h3 class=\"wp-block-heading\">L\u2019Agence europ\u00e9enne des m\u00e9dicaments approuve un traitement pour ralentir le d\u00e9clin cognitif dans certains cas d\u2019Alzheimer<\/h3>\n\n\n\n<p>L\u2019Agence europ\u00e9enne des m\u00e9dicaments (EMA) a annonc\u00e9 jeudi l\u2019approbation conditionnelle du traitement <strong>Leqembi<\/strong>, destin\u00e9 \u00e0 ralentir le d\u00e9clin cognitif chez les patients atteints de la maladie d\u2019Alzheimer. Ce traitement, d\u00e9velopp\u00e9 par les laboratoires japonais <strong>Eisai<\/strong> et am\u00e9ricain <strong>Biogen<\/strong>, avait initialement \u00e9t\u00e9 refus\u00e9 par l\u2019EMA en juillet dernier. Apr\u00e8s r\u00e9examen, l\u2019EMA estime d\u00e9sormais que les b\u00e9n\u00e9fices l\u2019emportent sur les risques pour une population cibl\u00e9e de patients.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Une recommandation pour une population sp\u00e9cifique<\/h4>\n\n\n\n<p>Le <strong>Leqembi<\/strong> est recommand\u00e9 pour des patients atteints d\u2019Alzheimer \u00e0 un stade pr\u00e9coce ou interm\u00e9diaire, n\u2019ayant pas encore atteint un stade avanc\u00e9 de la maladie. Toutefois, cette approbation concerne uniquement les patients pr\u00e9sentant un risque r\u00e9duit d\u2019h\u00e9morragies c\u00e9r\u00e9brales. Cela inclut ceux qui poss\u00e8dent <strong>une seule copie ou aucune copie du g\u00e8ne ApoE4<\/strong>, un facteur de risque important associ\u00e9 \u00e0 la maladie d\u2019Alzheimer. Selon l\u2019EMA, ces patients sont moins susceptibles de souffrir des effets secondaires graves identifi\u00e9s, notamment des saignements dans le cerveau.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Un revirement apr\u00e8s une \u00e9valuation approfondie<\/h4>\n\n\n\n<p>En juillet, l\u2019EMA avait rejet\u00e9 la mise sur le march\u00e9 du <strong>Leqembi<\/strong> dans l\u2019Union europ\u00e9enne. \u00c0 l\u2019\u00e9poque, l\u2019agence avait jug\u00e9 que les risques, en particulier les effets secondaires graves, surpassaient les b\u00e9n\u00e9fices observ\u00e9s lors des essais cliniques. Cependant, un r\u00e9examen a permis de conclure que le traitement pouvait \u00eatre b\u00e9n\u00e9fique pour une population sp\u00e9cifique, justifiant ainsi cette nouvelle recommandation.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Une reconnaissance internationale du Leqembi<\/h4>\n\n\n\n<p>Le <strong>Leqembi<\/strong> avait d\u00e9j\u00e0 \u00e9t\u00e9 autoris\u00e9 en <strong>janvier 2023 aux \u00c9tats-Unis<\/strong>, o\u00f9 il est prescrit aux patients \u00e0 un stade pr\u00e9coce de la maladie d\u2019Alzheimer. Depuis, le traitement a \u00e9galement \u00e9t\u00e9 commercialis\u00e9 au <strong>Japon<\/strong>, en <strong>Chine<\/strong> et au <strong>Royaume-Uni<\/strong> depuis ao\u00fbt dernier.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Comment fonctionne le Leqembi ?<\/h4>\n\n\n\n<p>Administr\u00e9 par intraveineuse toutes les deux semaines, le <strong>Leqembi<\/strong> agit en r\u00e9duisant les <strong>plaques amylo\u00efdes<\/strong> dans le cerveau, des accumulations anormales de prot\u00e9ines associ\u00e9es \u00e0 la progression de la maladie d\u2019Alzheimer. Les essais cliniques ont d\u00e9montr\u00e9 que ce traitement pouvait ralentir significativement le d\u00e9clin cognitif des patients cibl\u00e9s, offrant ainsi une lueur d\u2019espoir dans la prise en charge de cette maladie neurod\u00e9g\u00e9n\u00e9rative.<\/p>\n\n\n\n<p>Ce nouveau d\u00e9veloppement marque une avanc\u00e9e importante dans la recherche de solutions pour les personnes atteintes d\u2019Alzheimer. Toutefois, il rappelle \u00e9galement l&#8217;importance de continuer \u00e0 surveiller et \u00e9valuer les risques associ\u00e9s \u00e0 ces th\u00e9rapies innovantes.<\/p>","protected":false},"excerpt":{"rendered":"<p>L\u2019Agence europ\u00e9enne des m\u00e9dicaments approuve un traitement pour ralentir le d\u00e9clin cognitif dans certains cas d\u2019Alzheimer L\u2019Agence europ\u00e9enne des m\u00e9dicaments (EMA) a annonc\u00e9 jeudi l\u2019approbation conditionnelle du traitement Leqembi, destin\u00e9 \u00e0 ralentir le d\u00e9clin cognitif chez les patients atteints de la maladie d\u2019Alzheimer. Ce traitement, d\u00e9velopp\u00e9 par les laboratoires japonais Eisai et am\u00e9ricain Biogen, avait [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":4062,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4,29],"tags":[],"locatie":[27,26,28],"class_list":["post-4061","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actie-in-de-kijker","category-onderzoek","locatie-help-mee","locatie-homepage","locatie-over-alzheimer"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Un nouveau m\u00e9dicament approuv\u00e9 - Stop Alzheimer<\/title>\n<meta name=\"description\" content=\"Alzheimer : approbation du Leqembi, un traitement contre le d\u00e9clin cognitif li\u00e9 \u00e0 la maladie\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/stopalzheimer.be\/fr\/un-nouveau-medicament-approuve\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un nouveau m\u00e9dicament approuv\u00e9 - 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